Deadpool

First appearance of Deadpool — Wade Wilson debuts as a villain hired by Tolliver to attack Cable and the New Mutants. Rob Liefeld art. One of the most valuable comics of the 1990s.

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Facsimile reprint of Deadpool's first appearance — an exact reproduction of the original issue for modern collectors

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Second appearance of Deadpool — Cable transforms the New Mutants into X-Force. Deadpool lurks in the background as a recurring mercenary threat.

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Third appearance of Deadpool — battles X-Force directly. His personality begins to emerge as more comedic.

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Deadpool's first real spotlight — Domino storyline. Deadpool is hired to impersonate Domino, revealing his shapeshifting-like disguise skills.

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Second printing with gold cover — even the reprint is valuable due to the massive demand for Deadpool's first appearance

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Deadpool's first solo limited series — four issues by Fabian Nicieza and Joe Madureira. Deadpool hunts for Tolliver's will and its mysterious prize.

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Second solo limited series — four issues by Mark Waid and Ian Churchill. Deadpool vs Black Tom Cassidy and Juggernaut. Waid starts shaping Deadpool's humor.

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First ongoing solo series — Joe Kelly's legendary run begins. This is the series that defined Deadpool as we know him today. Introduces the humor, pathos, and fourth-wall breaking. Ed McGuinness art.

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Joe Kelly and Ed McGuinness launch the series that made Deadpool a star — establishes his internal monologue boxes, pop culture references, and tragic backstory

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"With Great Power Comes Great Coincidence" — Deadpool is transported into Amazing Spider-Man #47 from 1966. One of the most famous Deadpool issues ever. Fourth-wall breaking at its finest.

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Deadpool vs the Great Lakes Avengers — a hilarious team-up/fight that showcases Kelly's comedic genius

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Deadpool gets married — Wade marries Copycat (Vanessa Carlysle) in a surprisingly emotional issue

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Deadpool kills Wolverine — or does he? A time-travel storyline that plays with reality in classic Deadpool fashion

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Flashback issue — reveals Wade Wilson's early life as a mercenary before the Weapon X program. Part of Marvel's "Flashback Month."

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Deadpool's Weapon X origin explored — Wade's time in the Workshop, where failed Weapon X subjects were tortured and experimented on. Ajax (Francis) is his tormentor.

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Deadpool's relationship with Death — literally the Marvel entity Death. Thanos is jealous. The love triangle between Deadpool, Death, and Thanos is established.

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Deadpool vs Wolverine — reveals their shared history in the Weapon X program. Daniel Way writes their brutal first encounter.

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The legendary buddy series begins — Fabian Nicieza pairs Deadpool with Cable (Nathan Summers). Their odd couple dynamic becomes iconic. 50-issue run.

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Cable creates the island nation of Providence — Deadpool becomes his unlikely partner in trying to save the world

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Deadpool joins the Great Lakes Initiative — hilarious Civil War tie-in where Deadpool tries to register as a hero

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Final issue of the series — an emotional conclusion to Cable and Deadpool's partnership. Sets up both characters' future stories.

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Daniel Way's run begins — introduces the dual internal monologue boxes (white and yellow). Deadpool becomes a mainstream breakout hit. Secret Invasion tie-in.

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Deadpool vs Bullseye — two of Marvel's deadliest killers face off. Dark Reign tie-in.

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Deadpool goes to space — gets involved in a Secret Avengers storyline. Way expands Deadpool's world beyond Earth.

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Deadpool kills the Marvel Universe lead-up — a dark turn for the character

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Deadpool snaps and murders every hero and villain in the Marvel Universe — a darkly comedic limited series that became a massive hit. Cullen Bunn writes.

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Deadpool kills classic literary characters — after killing the Marvel Universe, he moves on to Moby Dick, Sherlock Holmes, and more

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The sequel — Deadpool is brainwashed into killing every Marvel hero again. Even more creative deaths.

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The trilogy conclusion — the Deadpool from "Kills the Marvel Universe" fights an army of Deadpool variants from across the multiverse

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Gerry Duggan and Brian Posehn's run begins — dead presidents of the United States come back as zombies and only Deadpool can stop them. Hilarious and heartfelt.

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Deadpool gets married (again) — Wade marries Shiklah, Queen of the Monsters, in a massive oversized issue with dozens of guest artists

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Deadpool's 250th issue celebration — the numbering combines all his series. A milestone event.

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Deadpool joins the Avengers — becomes a member of the Avengers Unity Division. A huge status upgrade for the character.

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Deadpool is an Avenger — Duggan continues with Deadpool balancing heroism, his mercenary nature, and his personal life. Mike Hawthorne art.

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Deadpool is ordered to kill Cable — his best friend. Secret Empire aftermath pushes Deadpool to his darkest point.

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Duggan's run finale — an emotional conclusion to the longest continuous Deadpool run in history. Wade hits rock bottom and finds his way back.

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Early Deadpool vs Wolverine battle — two regenerating killers clash. Adam Kubert art. A fan-favorite matchup.

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The unlikely buddy series — Spider-Man and Deadpool are forced to work together. Joe Kelly returns to write Deadpool. Became a massive hit.

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Deadpool and Thanos must team up — Death has gone missing and both of her suitors need to find her. Tim Seeley writes.

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The Merc with a Mouth vs the Ragin' Cajun — two fan-favorite characters clash in a con-artist caper

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Deadpool meets the aged Wolverine from the Old Man Logan timeline — two regenerators, very different worldviews

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Skottie Young's run — a fresh comedic take with Young's exaggerated art style. Deadpool is broke, divorced, and off the Avengers.

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Kelly Thompson's run — Deadpool becomes King of the Monsters after his ex-wife Shiklah's kingdom falls. A new direction.

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Alyssa Wong's run — Deadpool takes on a dangerous new villain while juggling his mercenary work. Fresh creative team.

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Rob Liefeld returns to draw Deadpool — the original creator reunites with his creation for a new limited series

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Cody Ziglar's run — timed with the Deadpool & Wolverine movie. Deadpool in a new era for Marvel Comics.

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